Most women notice sleep improvements within 1–2 weeks, while mood stability and cycle regulation typically occur within 4–6 weeks. Full hormonal balance may take 2–3 months of consistent use. Remember, you’re restoring years of hormone decline, so patience is key.

Yes. Bioidentical progesterone is molecularly identical to what your body produces naturally, making it safe for extended use. Unlike synthetic progestins, bioidentical progesterone works with your body’s natural processes. Always consult your healthcare provider for personalized guidance.

Wild yam contains diosgenin, which your body cannot convert to progesterone – that’s why they don’t work. Progesto-Life contains actual USP progesterone that’s bioidentical to your natural hormones, plus our micronization technology ensures superior absorption.

Absolutely. Many women in perimenopause still have periods but experience progesterone deficiency. Apply during your luteal phase (after ovulation) or as directed by your healthcare provider. The pump dosing makes it perfect for cycle-specific use.

Generally safe with most medications. However, consult your doctor if you’re taking blood thinners, seizure medications, or diabetes drugs. Many women successfully use progesterone cream alongside thyroid medications and other supplements.

Most progesterone creams fail due to poor absorption and inconsistent dosing. Our advanced micronization creates particles 10x smaller for superior absorption, while the pump delivers exactly 21mg every time. That’s why customers see results after other brands failed.

Yes, many fertility specialists recommend progesterone supplementation for women with low progesterone levels. Apply during your luteal phase to support implantation and early pregnancy. Always inform your doctor you’re using progesterone if you become pregnant.

Some women experience a brief adjustment period as hormone levels rebalance. This typically resolves within 1–2 weeks. Start with a smaller amount if concerned, and contact our hormone specialists for personalized guidance. Our 90-day guarantee ensures you're protected.